TY - JOUR A1 - Cichocki, J A A1 - Guyton, K Z A1 - Guha, N A1 - Chiu, W A A1 - Rusyn, I A1 - Lash, L H T1 - Target organ metabolism, toxicity, and mechanisms of trichloroethylene and perchloroethylene: key similarities, differences, and data gaps. Y1 - 2016/10/1 N1 - R835612 VL - 359 IS - 1 SP - 110 EP - 123 ER - TY - JOUR A1 - Cichocki, J A A1 - Furuya, S A1 - Konganti, K A1 - Luo, Y- S A1 - McDonald, T J A1 - Iwata, Y A1 - Chiu, W A A1 - Threadgill, D W A1 - Pogribny, I P A1 - Rusyn, I T1 - Impact of nonalcoholic fatty liver disease on toxicokinetics of tetrachloroethylene. Y1 - 2017/04/ N1 - R835612 VL - 361 IS - 1 SP - 17 EP - 28 ER - TY - JOUR A1 - Cichocki, J A A1 - Furuya, S A1 - Venkatratnam, A A1 - McDonald, T J A1 - Knap, A H A1 - Wade, T A1 - Sweet, S A1 - Chiu, W A A1 - Threadgill, D W A1 - Rusyn, I T1 - Characterization of variability in toxicokinetics and toxicodynamics of tetrachloroethylene using the Collaborative Cross mouse population. Y1 - 2017/05/30 N1 - R835612 VL - 125 IS - 5 SP - 057006 (12 pp.) ER - TY - JOUR A1 - Cichocki, J A A1 - Luo, Y S A1 - Furuya, S A1 - Venkatratnam, A A1 - Konganti, K A1 - Chiu, A1 - W, A A1 - Threadgill, D W A1 - Pogribny, I P T1 - Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice. Y1 - 2019/01/ N1 - R835612 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 167 IS - 1 SP - 126 EP - 137 ER - TY - JOUR A1 - Dalaijamts, C A1 - Cichocki, J A1 - Luo, Y A1 - Rusyn, I A1 - Chiu, W T1 - PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in mice Y1 - 2020//01 N1 - R835612 JF - TOXICOLOGY AND APPLIED PHARMACOLOGY J1 - TOXICOL APPL PHARM J2 - Toxicol.Appl.Pharmacol. J3 - Toxicol Appl Pharmacol J4 - Toxicology and Applied Pharmacology VL - 400 IS - 115069 ER - TY - JOUR A1 - Ferguson, K C A1 - Luo, Y S A1 - Rusyn, I A1 - Chiu, W A T1 - Comparative analysis of Rapid Equilibrium Dialysis (RED) and solid phase micro-extraction (SPME) methods for In Vitro-In Vivo extrapolation of environmental chemicals. Y1 - 2019/10/ N1 - R835612 JF - TOXICOLOGY IN VITRO J1 - TOXICOL IN VITRO VL - 60 SP - 245 EP - 251 ER - TY - JOUR A1 - Luo, Y A1 - Ferguson, K A1 - Rusyn, I A1 - Chiu, W T1 - In Vitro Bioavailability of the Hydrocarbon Fractions of Dimethyl Sulfoxide Extracts of Petroleum Substances Y1 - 2020//01 N1 - R835612 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 174 IS - 2 SP - 168 EP - 177 ER - TY - JOUR A1 - Rusyn, I A1 - Chiu, W A1 - Wright, F T1 - Model systems and organisms for addressing inter- and intra-species variability in risk assessment Y1 - 2022//01 N1 - R835612 JF - REGULATORY TOXICOLOGY AND PHARMACOLOGY J1 - REGUL TOXICOL PHARM J2 - Regulatory Toxicology and Pharmacology VL - 132 IS - 105197 ER - TY - JOUR A1 - Venkatratnam, A A1 - Furuya, S A1 - Kosyk, O A1 - Gold, A A1 - Bodnar, W A1 - Konganti, K A1 - Threadgill, D W A1 - Gillespie, K M A1 - Aylor, D L A1 - Wright, F A A1 - Chiu, W A A1 - Rusyn, I T1 - Collaborative Cross mouse population enables refinements to characterization of the variability in toxicokinetics of trichloroethylene and provides genetic evidence for the role of PPAR pathway in its oxidative metabolism. Y1 - 2017/03/27 N1 - R835612 VL - 158 IS - 1 SP - 48 EP - 62 ER -